Celecoxib-Loaded Solid Lipid Nanoparticles for Colon Delivery: Formulation Optimization and In Vitro Assessment of Anti-Cancer Activity

• Principais autores: Hamdan N. Alajami (Autor), Ehab A. Fouad (Autor), Abdelkader E. Ashour (Autor), Ashok Kumar (Autor), Alaa Eldeen B. Yassin (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2022-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

This work aimed to optimize a celecoxib (CXB)-loaded solid lipid nanoparticles (SLN) colon delivery system for the enhancement of anticancer activity. An ultrasonic melt-emulsification method was employed in this work for the preparation of SLN. The physical attributes were characterized for their p...