Curcumin and derivatives function through protein phosphatase 2A and presenilin orthologues in Dictyostelium discoideum

• Main Authors: Marco Cocorocchio (Author), Amy J. Baldwin (Author), Balint Stewart (Author), Lou Kim (Author), Adrian J. Harwood (Author), Christopher R. L. Thompson (Author), Paul L. R. Andrews (Author), Robin S. B. Williams (Author)
• Format: Book
• Published: The Company of Biologists, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Natural compounds often have complex molecular structures and unknown molecular targets. These characteristics make them difficult to analyse using a classical pharmacological approach. Curcumin, the main curcuminoid of turmeric, is a complex molecule possessing wide-ranging biological activities, c...