Exploring the Anticancer Effects of Brominated Plastoquinone Analogs with Promising Cytotoxic Activity in MCF-7 Breast Cancer Cells via Cell Cycle Arrest and Oxidative Stress Induction

• Main Authors: Ayse Tarbin Jannuzzi (Author), Ayse Mine Yilmaz Goler (Author), Nilüfer Bayrak (Author), Mahmut Yıldız (Author), Hatice Yıldırım (Author), Betul Karademir Yilmaz (Author), Deepak Shilkar (Author), Raghusrinivasan Jayaprakash Venkatesan (Author), Venkatesan Jayaprakash (Author), Amaç Fatih TuYuN (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Plastoquinone analogs are privileged structures among the known antiproliferative natural product-based compound families. Exploiting one of these analogs as a lead structure, we report the investigation of the brominated PQ analogs (BrPQ) in collaboration with the National Cancer Institute of Bethe...