JNK Signaling Pathway Mediates Acetaminophen-Induced Hepatotoxicity Accompanied by Changes of Glutathione S-Transferase A1 Content and Expression
Acetaminophen (APAP) is an analgesic-antipyretic drug and widely used in clinics. Its overdose may cause serious liver damage. Here, we examined the mechanistic role of c-Jun N-terminal kinase (JNK) signaling pathway in liver injury induced by different doses of APAP. Male mice were treated with APA...
Saved in:
Main Authors: | Chenxi Shi (Author), Beili Hao (Author), Yang Yang (Author), Ishfaq Muhammad (Author), Yuanyuan Zhang (Author), Yicong Chang (Author), Ying Li (Author), Changwen Li (Author), Rui Li (Author), Fangping Liu (Author) |
---|---|
Format: | Book |
Published: |
Frontiers Media S.A.,
2019-09-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Effects of C2-Ceramide and Oltipraz on Hepatocyte Nuclear Factor-1 and Glutathione S-Transferase A1 in Acetaminophen-Mediated Acute Mice Liver Injury
by: Xin Ma, et al.
Published: (2018) -
Glutathione S-Transferases in Cancer
by: Rahul Raj Singh, et al.
Published: (2021) -
Fluorine-thiol displacement probes for acetaminophen's hepatotoxicity
by: Benjamin L. Prather, et al.
Published: (2023) -
Glutathione Transferase (GST)-Activated Prodrugs
by: Andrea Calderan, et al.
Published: (2013) -
Glutathione S-transferase π: a potential role in antitumor therapy
by: Dong S, et al.
Published: (2018)