Phosphorus containing analogues of SAHA as inhibitors of HDACs

Phosphorus containing analogues of SAHA as inhibitors of HDACs

Histone deacetylases (HDACs) are a family of enzymes responsible for regulating DNA transcription by modulating its binding to histone proteins. HDACs are overexpressed in several types of cancers and are recognised as drug targets. Vorinostat, or suberanilohydroxamic acid (SAHA), is an histone deac...

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Bibliographic Details
Main Authors: Michael D. Pun (Author), Hsin-Hua Wu (Author), Feyisola P. Olatunji (Author), Britany N. Kesic (Author), John W. Peters (Author), Clifford E. Berkman (Author)
Format: Book
Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
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