Safety and Biodistribution of an Autologous Bone Marrow-Derived Mononuclear Cell Infusion into Renal Arteries in Patients with Focal Segmental Glomerulosclerosis: A Phase 1 Study

• Main Authors: Bruno Freire Botelho (Author), André Luis Barreira (Author), Marcio Gomes Filippo (Author), Karina Dutra Asensi (Author), Lanuza A P Faccioli (Author), Anna Beatriz dos Santos Salgado (Author), Elizabeth Figueiredo de Salles (Author), Carlos Eduardo Cruz Marques (Author), Pedro Leme Silva (Author), Regina Coeli dos Santos Goldenberg (Author), Angelo Maiolino (Author), Bianca Gutfilen (Author), Sergio Augusto Lopes de Souza (Author), Maurilo Leite Junior (Author), Marcelo Marcos Morales (Author)
• Format: Book
• Published: Hindawi Limited, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Patients with focal segmental glomerulosclerosis (FSGS) who are refractory to drug treatment may present progressive loss of kidney function, leading to chronic kidney disease stage 5 under dialysis treatment. The safety of systemic administration of bone marrow-derived mononuclear cells (BMDMCs) ha...