Systematic evaluation of PAXgene® tissue fixation for the histopathological and molecular study of lung cancer

• Main Authors: Mark Southwood (Author), Tomasz Krenz (Author), Natasha Cant (Author), Manisha Maurya (Author), Jana Gazdova (Author), Perry Maxwell (Author), Claire McGready (Author), Ellen Moseley (Author), Susan Hughes (Author), Peter Stewart (Author), Manuel Salto‐Tellez (Author), Daniel Groelz (Author), Doris Rassl (Author), On behalf of the STRATfix Consortium (Author)
• Format: Book
• Published: Wiley, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Whilst adequate for most existing pathological tests, formalin is generally considered a poor DNA preservative and use of alternative fixatives may prove advantageous for molecular testing of tumour material; an increasingly common approach to identify targetable driver mutations in lung ca...