CDX-301 prevents radiation-induced dysregulation of miRNA expression and biogenesis

• Main Authors: Dharmendra Kumar Soni (Author), Vidya P. Kumar (Author), Shukla Biswas (Author), Gregory P. Holmes-Hampton (Author), Sharmistha Bhattacharyya (Author), Lawrence J. Thomas (Author), Roopa Biswas (Author), Sanchita P. Ghosh (Author)
• Format: Book
• Published: Elsevier, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Risks of radiation exposure necessitate the development of radioprophylactic drugs. We have reported the efficacy of CDX-301, a recombinantly developed human protein form of Fms-related tyrosine kinase 3 ligand (Flt3L), as a radioprophylactic and radiomitigatory agent. Here, we performed global micr...