Characterization of pathological remodeling in the chronic atrioventricular block cynomolgus monkey heart

• Main Authors: Hiroko Izumi-Nakaseko (Author), Kengo Sakamoto (Author), Ai Goto (Author), Ryuichi Kambayashi (Author), Akio Matsumoto (Author), Yoshinori Takei (Author), Akira Takahara (Author), Atsushi Sugiyama (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We studied time course of pathological remodeling occurring in the cynomolgus monkey hearts against persistent atrioventricular block condition (n = 10). The atrioventricular block induced the ventricular and atrial dilation followed by the ventricular hypertrophy. Interstitial fibrosis in the ventr...