Antioxidant Activity of Fluoxetine and Vortioxetine in a Non-Transgenic Animal Model of Alzheimer's Disease

• Main Authors: Giuseppe Caruso (Author), Margherita Grasso (Author), Annamaria Fidilio (Author), Sebastiano Alfio Torrisi (Author), Nicolò Musso (Author), Federica Geraci (Author), Maria Rosaria Tropea (Author), Anna Privitera (Author), Fabio Tascedda (Author), Daniela Puzzo (Author), Salvatore Salomone (Author), Filippo Drago (Author), Gian Marco Leggio (Author), Filippo Caraci (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Depression is a risk factor for the development of Alzheimer's disease (AD). A neurobiological and clinical continuum exists between AD and depression, with neuroinflammation and oxidative stress being involved in both diseases. Second-generation antidepressants, in particular selective seroton...