Bombesin-like receptor 3 (Brs3) expression in glutamatergic, but not GABAergic, neurons is required for regulation of energy metabolism

• Main Authors: Cuiying Xiao (Author), Ramón A. Piñol (Author), Jesse Lea Carlin (Author), Cuiling Li (Author), Chuxia Deng (Author), Oksana Gavrilova (Author), Marc L. Reitman (Author)
• Format: Book
• Published: Elsevier, 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Bombesin-like receptor 3 (BRS-3) is an orphan G protein-coupled receptor. Brs3 null mice have reduced resting metabolic rate and body temperature, increased food intake, and obesity. Here we study the role of Brs3 in different neuron types. Methods: Mice able to undergo Cre recombinase-de...