Genomic alteration discordance in the paired primary-recurrent ovarian cancers: based on the comprehensive genomic profiling (CGP) analysis

• Main Authors: Jiayin Dong (Author), Jing Ni (Author), Jiahui Chen (Author), Xuening Wang (Author), Luxin Ye (Author), Xia Xu (Author), Wenwen Guo (Author), Xiaoxiang Chen (Author)
• Format: Book
• Published: BMC, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Purpose Ovarian cancer (OC) is characterized by a high recurrence rate, and homologous recombination deficiency (HRD) is an important biomarker in the clinical management of OC. We investigated the differences in clinical genomic profiles between the primary and platinum-sensitive recurrent...