Curcumin and berberine co-loaded liposomes for anti-hepatocellular carcinoma therapy by blocking the cross-talk between hepatic stellate cells and tumor cells

• Main Authors: Jingliang Wu (Author), Cuiping Qi (Author), Hao Wang (Author), Qing Wang (Author), Jingui Sun (Author), Jinping Dong (Author), Guohua Yu (Author), Zhiqin Gao (Author), Bo Zhang (Author), Guixiang Tian (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cancer-associated fibroblasts (CAFs) are a major component of the tumor microenvironment (TME). In hepatocellular carcinoma (HCC), quiescent hepatic stellate cells (HSCs) could be activated to become CAFs, which play a critical role in tumor progression and drug resistance. Therefore, recent efforts...