CuMV VLPs Containing the RBM from SARS-CoV-2 Spike Protein Drive Dendritic Cell Activation and Th1 Polarization

• Main Authors: Ana Isabel Sebastião (Author), Daniela Mateus (Author), Mylène A. Carrascal (Author), Cátia Sousa (Author), Luísa Cortes (Author), Martin F. Bachmann (Author), Anália do Carmo (Author), Ana Miguel Matos (Author), Maria Goreti F. Sales (Author), Maria Teresa Cruz (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dendritic cells (DCs) are the most specialized and proficient antigen-presenting cells. They bridge innate and adaptive immunity and display a powerful capacity to prime antigen-specific T cells. The interaction of DCs with the receptor-binding domain of the spike (S) protein from the severe acute r...