Pathways of 4-Hydroxy-2-Nonenal Detoxification in a Human Astrocytoma Cell Line

• Main Authors: Eleonora Peroni (Author), Viola Scali (Author), Francesco Balestri (Author), Mario Cappiello (Author), Umberto Mura (Author), Antonella Del Corso (Author), Roberta Moschini (Author)
• Format: Book
• Published: MDPI AG, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

One of the consequences of the increased level of oxidative stress that often characterizes the cancer cell environment is the abnormal generation of lipid peroxidation products, above all 4-hydroxynonenal. The contribution of this aldehyde to the pathogenesis of several diseases is well known. In t...