Involvement of Inflammasome Components in Kidney Disease

• Main Authors: Ana Karina Aranda-Rivera (Author), Anjali Srivastava (Author), Alfredo Cruz-Gregorio (Author), José Pedraza-Chaverri (Author), Shrikant R. Mulay (Author), Alexandra Scholze (Author)
• Format: Book
• Published: MDPI AG, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inflammasomes are multiprotein complexes with an important role in the innate immune response. Canonical activation of inflammasomes results in caspase-1 activation and maturation of cytokines interleukin-1β and -18. These cytokines can elicit their effects through receptor activation, both locally...