Involvement of Inflammasome Components in Kidney Disease

• Hoofdauteurs: Ana Karina Aranda-Rivera (Auteur), Anjali Srivastava (Auteur), Alfredo Cruz-Gregorio (Auteur), José Pedraza-Chaverri (Auteur), Shrikant R. Mulay (Auteur), Alexandra Scholze (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2022-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Inflammasomes are multiprotein complexes with an important role in the innate immune response. Canonical activation of inflammasomes results in caspase-1 activation and maturation of cytokines interleukin-1β and -18. These cytokines can elicit their effects through receptor activation, both locally...