Stachydrine is effective and selective against blast phase chronic myeloid leukaemia through inhibition of multiple receptor tyrosine kinases

• Những tác giả chính: Ruixin Gu (Tác giả), Wei Zhang (Tác giả), Dandan Xu (Tác giả)
• Định dạng: Sách
• Được phát hành: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Context Resistance to BCR-ABL tyrosine kinase inhibitor (TKI) is the cause of treatment failure in blast phase chronic myeloid leukaemia (BP-CML). Agents that act synergistically with BCR-ABL TKI are required to improve response.Objective This work investigated the effects of stachydrine in CML.Mate...