Conceptual causal framework to assess the effect of SARS-CoV-2 variants on COVID-19 disease severity among hospitalized patients

• Main Authors: Nina Van Goethem (Author), Ben Serrien (Author), Mathil Vandromme (Author), Chloé Wyndham-Thomas (Author), Lucy Catteau (Author), Ruben Brondeel (Author), Sofieke Klamer (Author), Marjan Meurisse (Author), Lize Cuypers (Author), Emmanuel André (Author), Koen Blot (Author), Herman Van Oyen (Author)
• Format: Book
• Published: BMC, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background SARS-CoV-2 strains evolve continuously and accumulate mutations in their genomes over the course of the pandemic. The severity of a SARS-CoV-2 infection could partly depend on these viral genetic characteristics. Here, we present a general conceptual framework that allows to stud...