The pivotal role of 5-lipoxygenase-derived LTB4 in controlling pulmonary paracoccidioidomycosis.

• Main Authors: Patrícia Campi Santos (Author), Daniel Assis Santos (Author), Lucas Secchim Ribeiro (Author), Caio Tavares Fagundes (Author), Talles Prosperi de Paula (Author), Thiago Vinícius Avila (Author), Ludmila de Matos Baltazar (Author), Mila Moreira Madeira (Author), Rosana de Carvalho Cruz (Author), Ana Carolina Fialho Dias (Author), Fabiana Simão Machado (Author), Mauro Martins Teixeira (Author), Patrícia Silva Cisalpino (Author), Danielle G Souza (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leukotrienes (LTs) produced from arachidonic acid by the action of 5-lipoxygenase (5-LO) are classical mediators of inflammatory responses. However, studies published in the literature regarding these mediators are contradictory and it remains uncertain whether these lipid mediators play a role in h...