PD-L1 expression correlated with p53 expression in oral squamous cell carcinoma

• Main Authors: Itaru Tojyo (Author), Yukari Shintani (Author), Takashi Nakanishi (Author), Kenjiro Okamoto (Author), Yukihiro Hiraishi (Author), Shigeyuki Fujita (Author), Mayu Enaka (Author), Fuyuki Sato (Author), Yasuteru Muragaki (Author)
• Format: Book
• Published: SpringerOpen, 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Programmed cell death ligand 1 (PD-L1) is an immune checkpoint molecule that attenuates the immune response. PD-L1 contributes to failed antitumor immunity; thereby, blockade of PD-L1 with monoclonal antibody enhances the immune response. Recently, it was reported that PD-L1 was...