Development of a Personalized Tumor Neoantigen Based Vaccine Formulation (FRAME-001) for Use in a Phase II Trial for the Treatment of Advanced Non-Small Cell Lung Cancer

Development of a Personalized Tumor Neoantigen Based Vaccine Formulation (FRAME-001) for Use in a Phase II Trial for the Treatment of Advanced Non-Small Cell Lung Cancer

Stage III-IV non-small cell lung cancer (NSCLC) is a devastating disease characterized by a poor prognosis. NSCLC tumors carry genetic mutations, which can lead to the expression of altered protein sequences. Peptides originating from mutated proteins and bound to MHC molecules on the tumor cell sur...

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Main Authors: Linette T. Oosting (Author), Katka Franke (Author), Michael V. Martin (Author), Wigard P. Kloosterman (Author), Jennifer A. Jamieson (Author), Laura A. Glenn (Author), Miranda W. de Jager (Author), Jacoba van Zanten (Author), Derk P. Allersma (Author), Bahez Gareb (Author)
Format: Book
Published: MDPI AG, 2022-07-01T00:00:00Z.
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3rd Floor Main Library

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