Interaction of Signaling Lymphocytic Activation Molecule Family 1 (SLAMF1) receptor with Trypanosoma cruzi is strain-dependent and affects NADPH oxidase expression and activity.

• Main Authors: Cristina Poveda (Author), Alfonso Herreros-Cabello (Author), Francisco Callejas-Hernández (Author), Jesús Osuna-Pérez (Author), María C Maza (Author), Carlos Chillón-Marinas (Author), Jossela Calderón (Author), Konstantinos Stamatakis (Author), Manuel Fresno (Author), Núria Gironès (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The receptor Signaling Lymphocyte-Activation Molecule Family 1 (SLAMF1) controls susceptibility to Infection by the lethal Trypanosoma cruzi Y strain. To elucidate whether genetic diversity of the parasite was related with disease susceptibility, we further analyzed the role of SLAMF1 using 6 differ...