Systematic evaluation for the causal effects of blood metabolites on osteoporosis: Genetic risk score and Mendelian randomization

PurposeOsteoporosis is associated with metabolic alterations, but the causal roles of serum metabolites on osteoporosis have not been identified.MethodsBased on the large individual-level datasets from UK Biobank as well as GWAS summary datasets, we first constructed genetic risk scores (GRSs) for 3...

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Main Authors: Xing-Hao Yu (Author), Rong-Rong Cao (Author), Yi-Qun Yang (Author), Lei Zhang (Author), Shu-Feng Lei (Author), Fei-Yan Deng (Author)
Format: Book
Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
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