SIS3 alleviates cisplatin-induced acute kidney injury by regulating the lncRNA Arid2-IR-transferrin receptor pathway

• Main Authors: Jiayan Huang (Author), Weiyan Lai (Author), Ming Li (Author), Canming Li (Author), Tanqi Lou (Author), Hui Peng (Author), Zengchun Ye (Author)
• Format: Book
• Published: Karger Publishers, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: TGF-β/Smad3 may be involved in the pathogenesis of acute kidney injury (AKI), but its functional role and mechanism of action in cisplatin-induced AKI are unclear. Here, we established a cisplatin-induced AKI mouse model to demonstrate that Smad3 may have roles in cisplatin nephropathy...