Safety, tolerability, and pharmacokinetics of repeated oral doses of 2-hydroxybenzylamine acetate in healthy volunteers: a double-blind, randomized, placebo-controlled clinical trial

• Main Authors: Lisa M. Pitchford (Author), Patricia M. Driver (Author), John C. Fuller (Author), Wendell S. Akers (Author), Naji N. Abumrad (Author), Venkataraman Amarnath (Author), Ginger L. Milne (Author), Sheau-Chiann Chen (Author), Fei Ye (Author), L. Jackson Roberts (Author), M. Benjamin Shoemaker (Author), John A. Oates (Author), John A. Rathmacher (Author), Olivier Boutaud (Author)
• Format: Book
• Published: BMC, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background 2-Hydroxybenzylamine (2-HOBA) is a selective dicarbonyl electrophile scavenger being developed as a nutritional supplement to help protect against the development of conditions associated with dicarbonyl electrophile formation, such as the cognitive decline observed with Mild Cog...