Chemopreventive Effects of Silibinin on Colitis-Associated Tumorigenesis by Inhibiting IL-6/STAT3 Signaling Pathway

• Main Authors: Rongjuan Zheng (Author), Jiaheng Ma (Author), Dan Wang (Author), Wenxiao Dong (Author), Sinan Wang (Author), Tianyu Liu (Author), Runxiang Xie (Author), Li Liu (Author), Bangmao Wang (Author), Hailong Cao (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inflammatory bowel disease (IBD), characterized by sustained inflammation, is a latent risk factor of colon tumorigenesis. Silibinin has been reported to be anti-inflammatory and antineoplastic, but its efficacy on colitis-associated cancer (CAC) has not been reported. Interlukin-6/signal transducer...