Innate immune responses and antioxidant/oxidant imbalance are major determinants of human Chagas disease.

• Main Authors: Monisha Dhiman (Author), Yun A Coronado (Author), Cecilia K Vallejo (Author), John R Petersen (Author), Adetoun Ejilemele (Author), Sonia Nuñez (Author), Maria Paola Zago (Author), Heidi Spratt (Author), Nisha Jain Garg (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We investigated the pathological and diagnostic role of selected markers of inflammation, oxidant/antioxidant status, and cellular injury in human Chagas disease.Seropositive/chagasic subjects characterized as clinically-symptomatic or clinically-asymptomatic (n = 116), seronegative/cardiac subjects...