Vam3, a compound derived from Vitis amurensis Rupr., attenuated colitis-related tumorigenesis by inhibiting NF-κB signaling pathway

• Main Authors: Lingling Xuan (Author), Rentao Jiang (Author), Zhiyuan Wu (Author), Honggan Yi (Author), Chunsuo Yao (Author), Qi Hou (Author), Chunfeng Qu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Chronic inflammation is one of the important mediators of colitis-related colon cancer (CRC). Abundant mast cells (MCs) were observed in the tumor microenvironment and mediators released upon MC activation play an important role in the process of chronic inflammation. Previously, we foun...