Antidepressant-like activity of a brain penetrant HCN channel inhibitor in mice

Antidepressant-like activity of a brain penetrant HCN channel inhibitor in mice

Changes in Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) channel function have been linked to depressive-like traits, making them potential drug targets. However, there is currently no peer-reviewed data supporting the use of a small molecule modulator of HCN channels in depression treat...

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Main Authors: Paulo Pinares-Garcia (Author), James Spyrou (Author), Chaseley E. McKenzie (Author), Ian C. Forster (Author), Ming S. Soh (Author), Erlina Mohamed Syazwan (Author), Mohammed Atif (Author), Christopher A. Reid (Author)
Format: Book
Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
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3rd Floor Main Library

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