Rapid, low cost and sensitive detection of Calreticulin mutations by a PCR based amplicon length differentiation assay for diagnosis of myeloproliferative neoplasms

Rapid, low cost and sensitive detection of Calreticulin mutations by a PCR based amplicon length differentiation assay for diagnosis of myeloproliferative neoplasms

Abstract Background Calreticulin (CALR) gene mutations are currently recommended as biomarkers in diagnosis of patients with myeloproliferative neoplasms (MPN) with Jak2 V617F negative phenotype. Our aim was to establish a rapid, low cost and sensitive assay for identification of CALR gene mutations...

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Main Authors: Ngo Tat Trung (Author), Dao Thanh Quyen (Author), Nghiem Xuan Hoan (Author), Dao Phuong Giang (Author), Tran Thi Huyen Trang (Author), Thirumalaisamy P. Velavan (Author), Mai Hong Bang (Author), Le Huu Song (Author)
Format: Book
Published: BMC, 2019-06-01T00:00:00Z.
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