Ultrasonic Microbubble Cavitation Deliver Gal-3 shRNA to Inhibit Myocardial Fibrosis after Myocardial Infarction

• Main Authors: Wenqu Li (Author), Qiaofeng Jin (Author), Li Zhang (Author), Shukun He (Author), Yishu Song (Author), Lingling Xu (Author), Cheng Deng (Author), Lufang Wang (Author), Xiaojuan Qin (Author), Mingxing Xie (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Galectin-3 (Gal-3) participates in myocardial fibrosis (MF) in a variety of ways. Inhibiting the expression of Gal-3 can effectively interfere with MF. This study aimed to explore the value of Gal-3 short hairpin RNA (shRNA) transfection mediated by ultrasound-targeted microbubble destruction (UTMD)...