Involvement of Toll Like Receptor 2 Signaling in Secondary Injury during Experimental Diffuse Axonal Injury in Rats

• Main Authors: Yonglin Zhao (Author), Junjie Zhao (Author), Ming Zhang (Author), Yahui Zhao (Author), Jiaxi Li (Author), Xudong Ma (Author), Tingqin Huang (Author), Honggang Pang (Author), Bo Wang (Author), Jinning Song (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Treatment of diffuse axonal injury (DAI) remains challenging in clinical practice due to the unclear pathophysiological mechanism. Uncontrolled, excessive inflammation is one of the most recognized mechanisms that contribute to the secondary injury after DAI. Toll like receptor 2 (TLR2) is highlight...