Impact of benznidazole treatment on the functional response of Trypanosoma cruzi antigen-specific CD4+CD8+ T cells in chronic Chagas disease patients.

• Main Authors: Elena Pérez-Antón (Author), Adriana Egui (Author), M Carmen Thomas (Author), Concepción J Puerta (Author), John Mario González (Author), Adriana Cuéllar (Author), Manuel Segovia (Author), Manuel Carlos López (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chagas disease is caused by Trypanosoma cruzi. The persistence of the parasite is associated with the disease chronicity and the impairment of the cellular immune response. It has been reported that the CD4+CD8+ T cell population expands in chronic Chagas disease patients. Few studies have focused o...