Da-Bu-Yin-Wan Improves the Ameliorative Effect of DJ-1 on Mitochondrial Dysfunction Through Augmenting the Akt Phosphorylation in a Cellular Model of Parkinson's Disease

• Main Authors: Yi Zhang (Author), Xiao-Gang Gong (Author), Hong-Mei Sun (Author), Zhen-Yu Guo (Author), Jing-Hong Hu (Author), Yuan-Yuan Wang (Author), Wan-Di Feng (Author), Lin Li (Author), Ping Li (Author), Zhen-Zhen Wang (Author), Nai-Hong Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Da-Bu-Yin-Wan (DBYW) is recorded originally in China over six centuries ago, and it is used to treat Parkinson's disease (PD) clinically in recent decades. DJ-1 is a homodimeric protein linked to early-onset PD, and found in the mitochondria. In addition, DJ-1 could protect the cells by regulat...