Oxygen Tension Strongly Influences Metabolic Parameters and the Release of Interleukin-6 of Human Amniotic Mesenchymal Stromal Cells In Vitro

• Main Authors: Asmita Banerjee (Author), Andrea Lindenmair (Author), Ralf Steinborn (Author), Sergiu Dan Dumitrescu (Author), Simone Hennerbichler (Author), Andrey V. Kozlov (Author), Heinz Redl (Author), Susanne Wolbank (Author), Adelheid Weidinger (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The human amniotic membrane (hAM) has been used for tissue regeneration for over a century. In vivo (in utero), cells of the hAM are exposed to low oxygen tension (1-4% oxygen), while the hAM is usually cultured in atmospheric, meaning high, oxygen tension (20% oxygen). We tested the influence of ox...