Supplementing clinical lactation studies with PBPK modeling to inform drug therapy in lactating mothers: Prediction of primaquine exposure as a case example
Abstract Evaluating the safety of primaquine (PQ) during breastfeeding requires an understanding of its pharmacokinetics (PKs) in breast milk and its exposure in the breastfed infant. Physiologically‐based PK (PBPK) modeling is primed to assess the complex interplay of factors affecting the exposure...
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Format: | Book |
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Wiley,
2024-03-01T00:00:00Z.
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A1234.567 |
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