Sonoporation of the Round Window Membrane on a Sheep Model: A Safety Study

• Main Authors: Sandrine Kerneis (Author), Jean-Michel Escoffre (Author), John J. Galvin (Author), Ayache Bouakaz (Author), Antoine Presset (Author), Corentin Alix (Author), Edward Oujagir (Author), Antoine Lefèvre (Author), Patrick Emond (Author), Hélène Blasco (Author), David Bakhos (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sonoporation using microbubble-assisted ultrasound increases the permeability of a biological barrier to therapeutic molecules. Application of this method to the round window membrane could improve the delivery of therapeutics to the inner ear. The aim of this study was to assess the safety of sonop...