Improved Olfactory Deposition of Theophylline Using a Nanotech Soft Mist Nozzle Chip

• Main Authors: Madeline X. Zhang (Author), Frank Verhoeven (Author), Pieter Ravensbergen (Author), Stefan Kooij (Author), Rick Geoffrion (Author), Daniel Bonn (Author), Cees J. M. van Rijn (Author)
• Format: Book
• Published: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Currently, nasal administration of active pharmaceutical ingredients is most commonly performed using swirl-nozzle-based pump devices or pressurized syringes. However, they lead to limited deposition in the more active regions of the nasal cavity, especially the olfactory region, which is crucial fo...