Dose-response technique combined with stable isotope tracing for drug metabolite profiling by using high-resolution mass spectrometry

• मुख्य लेखकों: I-Shou Lin (लेखक), Chia-Ying Anderin Chuang (लेखक), Chia-Lung Shih (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2023-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: Mass spectrometry metabolomics-based data-processing approaches have been developed for drug metabolite profiling. However, existing approaches cannot be used to comprehensively identify drug metabolites with high efficacy.Methods: Herein, we propose a two-stage data-processing approach...