Dose-response technique combined with stable isotope tracing for drug metabolite profiling by using high-resolution mass spectrometry

• Asıl Yazarlar: I-Shou Lin (Yazar), Chia-Ying Anderin Chuang (Yazar), Chia-Lung Shih (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2023-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Background: Mass spectrometry metabolomics-based data-processing approaches have been developed for drug metabolite profiling. However, existing approaches cannot be used to comprehensively identify drug metabolites with high efficacy.Methods: Herein, we propose a two-stage data-processing approach...