New Approaches for Basophil Activation Tests Employing Dendrimeric Antigen-Silica Nanoparticle Composites

• Main Authors: Silvia Calvo-Serrano (Author), Esther Matamoros (Author), Jose Antonio Céspedes (Author), Rubén Fernández-Santamaría (Author), Violeta Gil-Ocaña (Author), Ezequiel Perez-Inestrosa (Author), Cecilia Frecha (Author), Maria I. Montañez (Author), Yolanda Vida (Author), Cristobalina Mayorga (Author), Maria J. Torres (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In vitro cell activation through specific IgE bound to high-affinity receptors on the basophil surface is a widely used strategy for the evaluation of IgE-mediated immediate hypersensitivity reactions to betalactams. Cellular activation requires drug conjugation to a protein to form a large enough s...