Molecular Mechanism of Naringenin Against High-Glucose-Induced Vascular Smooth Muscle Cells Proliferation and Migration Based on Network Pharmacology and Transcriptomic Analyses

• Main Authors: Wenjun He (Author), Yanming Wang (Author), Rui Yang (Author), Huihui Ma (Author), Xuqing Qin (Author), Meijuan Yan (Author), Yi Rong (Author), Yufang Xie (Author), Li Li (Author), Junqiang Si (Author), Xinzhi Li (Author), Ketao Ma (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although the protective effects of naringenin (Nar) on vascular smooth muscle cells (VSMCs) have been confirmed, whether it has anti-proliferation and anti-migration effects in high-glucose-induced VSMCs has remained unclear. This study aimed to clarify the potential targets and molecular mechanism...