Injection of hybrid 3D spheroids composed of podocytes, mesenchymal stem cells, and vascular endothelial cells into the renal cortex improves kidney function and replenishes glomerular podocytes

• Main Authors: Wen‐Yu Yang (Author), Li‐Chi Chen (Author), Ya‐Ting Jhuang (Author), Yu‐Jie Lin (Author), Pei‐Yu Hung (Author), Yi‐Ching Ko (Author), Meng‐Yu Tsai (Author), Yun‐Wei Lee (Author), Li‐Wen Hsu (Author), Chih‐Kuang Yeh (Author), Hsiang‐Hao Hsu (Author), Chieh‐Cheng Huang (Author)
• Format: Book
• Published: Wiley, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Podocytes are highly differentiated epithelial cells that are crucial for maintaining the glomerular filtration barrier in the kidney. Podocyte injury followed by depletion is the major cause of pathological progression of kidney diseases. Although cell therapy has been considered a promisi...