Enantioselective Interactions of Anti-Infective 8-Aminoquinoline Therapeutics with Human Monoamine Oxidases A and B

• Asıl Yazarlar: Narayan D. Chaurasiya (Yazar), Haining Liu (Yazar), Robert J. Doerksen (Yazar), N. P. Dhammika Nanayakkara (Yazar), Larry A. Walker (Yazar), Babu L. Tekwani (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

8-Aminoquinolines (8-AQs) are an important class of anti-infective therapeutics. The monoamine oxidases (MAOs) play a key role in metabolism of 8-AQs. A major role for MAO-A in metabolism of primaquine (PQ), the prototypical 8-AQ antimalarial, has been demonstrated. These investigations were further...