The Anti-Depressive Effects of Hesperidin and the Relative Mechanisms Based on the NLRP3 Inflammatory Signaling Pathway

• Main Authors: Lulu Xie (Author), Zhimin Gu (Author), Haizhao Liu (Author), Beitian Jia (Author), Yiyang Wang (Author), Min Cao (Author), Ruiwen Song (Author), Zhaiyi Zhang (Author), Yuhong Bian (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is increasing evidence showing that inflammation is associated with depression in humans. Hesperidin, a natural bioflavonoid, has performed excellent effects on depression. The aim of this research was to investigate the therapeutic effect of hesperidin on chronic unpredictable mild stress (CUM...