Polyketides and alkaloids from the fungus Aspergillus Fumigatus YB4-17 and ent-Fumiquinazoline J induce apoptosis, paraptosis in human hepatoma HepG2 cells

• Main Authors: Huannan Wang (Author), Lixiang Sun (Author), Xueyang Ma (Author), Shihao Jin (Author), Yidan Xi (Author), Chunmei Sai (Author), Maocai Yan (Author), Zhongbin Cheng (Author), Zhen Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatocellular carcinoma (HCC) is one of the most common malignancies. The currently available clinical drugs for HCC frequently cause serious side effects and the treatment outcomes are unsatisfactory. It is urgent to develop effective drugs with high selectivity and low adverse effects for HCC. Me...