Niuhuang Qingxin Wan ameliorates depressive-like behaviors and improves hippocampal neurogenesis through modulating TrkB/ERK/CREB signaling pathway in chronic restraint stress or corticosterone challenge mice

• Autors principals: Qiaohui Du (Autor), Chong Gao (Autor), Bun Tsoi (Autor), Meiling Wu (Autor), Jiangang Shen (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Introduction: Chronic stress-associated hormonal imbalance impairs hippocampal neurogenesis, contributing to depressive and anxiety behaviors. Targeting neurogenesis is thus a promising antidepressant therapeutic strategy. Niuhuang Qingxin Wan (NHQXW) is an herbal formula for mental disorders in Tra...