Niuhuang Qingxin Wan ameliorates depressive-like behaviors and improves hippocampal neurogenesis through modulating TrkB/ERK/CREB signaling pathway in chronic restraint stress or corticosterone challenge mice

• Hauptverfasser: Qiaohui Du (VerfasserIn), Chong Gao (VerfasserIn), Bun Tsoi (VerfasserIn), Meiling Wu (VerfasserIn), Jiangang Shen (VerfasserIn)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2024-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Introduction: Chronic stress-associated hormonal imbalance impairs hippocampal neurogenesis, contributing to depressive and anxiety behaviors. Targeting neurogenesis is thus a promising antidepressant therapeutic strategy. Niuhuang Qingxin Wan (NHQXW) is an herbal formula for mental disorders in Tra...