Inhibition of miR-128-3p by Tongxinluo Protects Human Cardiomyocytes from Ischemia/reperfusion Injury via Upregulation of p70s6k1/p-p70s6k1

• Main Authors: Gui-hao Chen (Author), Chuan-sheng Xu (Author), Jie Zhang (Author), Qing Li (Author), He-he Cui (Author), Xiang-dong Li (Author), Li-ping Chang (Author), Rui-jie Tang (Author), Jun-yan Xu (Author), Xia-qiu Tian (Author), Pei-sen Huang (Author), Jun Xu (Author), Chen Jin (Author), Yue-jin Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Aims: Tongxinluo (TXL) is a multifunctional traditional Chinese medicine that has been widely used to treat cardiovascular and cerebrovascular diseases. However, no studies have explored whether TXL can protect human cardiomyocytes (HCMs) from ischemia/reperfusion (I/R) injury. Reperf...