Discovery of New Uracil and Thiouracil Derivatives as Potential HDAC Inhibitors

• Main Authors: Omnia R. Elbatrawy (Author), Mohamed Hagras (Author), Moshira A. El Deeb (Author), Fatimah Agili (Author), Maghawry Hegazy (Author), Ahmed A. El-Husseiny (Author), Mahmoud Mohamed Mokhtar (Author), Samy Y. Elkhawaga (Author), Ibrahim H. Eissa (Author), Samar El-Kalyoubi (Author)
• Format: Book
• Published: MDPI AG, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<b>Background</b>: Histone deacetylase inhibitors (HDACIs) are a relatively new class of potential drugs for treating cancer. <b>Aim</b>: Discovery of new anticancer agents targeting HDAC. <b>Methods</b>: New uracil and thiouracil derivatives panels were designed...