Aminoglycosides in the Intensive Care Unit: What Is New in Population PK Modeling?

• Main Authors: Alexandre Duong (Author), Chantale Simard (Author), Yi Le Wang (Author), David Williamson (Author), Amélie Marsot (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Although aminoglycosides are often used as treatment for Gram-negative infections, optimal dosing regimens remain unclear, especially in ICU patients. This is due to a large between- and within-subject variability in the aminoglycoside pharmacokinetics in this population. Objective: This...