Drug disposition in cholestasis: An important concern
Abstract Cholestasis, a chronic liver condition, disrupts bile acid homeostasis and complicates drug disposition, posing significant challenges in medicating cholestatic patients. Drug metabolism enzymes and transporters (DMETs) are pivotal in drug clearance. Research indicates that cholestasis lead...
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Wiley,
2024-08-01T00:00:00Z.
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